| Early examples of organic reactions and applications were serendipitous, such as Perkin's accidental | | |
| However, from the 20th century, the progress of organic | | |
| It allowed for synthesis of specifically selected compounds or even molecules designed with specific | | |
| The process of finding new synthesis routes for a given compounds is called | | |
| Total synthesis of complex natural compounds started with urea, increased in | | |
| In 1907 total synthesis was commercialized the first time by | | |
| Pharmaceutical benefits have been substantial, for example cholesterol-related compounds have opened ways to | | |
